Nanomaterials for cell expansion
- Providing physical and biochemical cues
- Reducing expensive reagents
- Focus on immunotherapy
- Treg and CAR T expansion
Biomaterials, 140 (2017) 58-68.
Cell-instructive scaffolds
- Nanostructured scaffolds
- Limbal cell delivery
- Islet delivery
- Endothelial progenitor cell delivery
- Surface chemistry key to success
Biomaterials, 30 (2009), 2873-2880; Journal of Materials Chemistry B, 5 (2017), 220-225.
High throughput screening
- Cell microarrays and gradients
- Identify optimal surfaces that mimic in vivo environment
- Reduce expensive reagents
- Plasma polymer coatings
- Pore size gradients
- Translation and scale-up
Advanced Functional Materials, 25 (2015), 2737-2744; Lab on a Chip. 17 (2017), 501 – 510.
Smart Petri dish
- Biosensors to assess cell quality
- In situ detection of cell metabolites or contaminants
- Work in cell culture media and compatible with bioreactors
- Electrochemical or optical transducers
Biosensors and Bioelectronics, 91 (2017) 515-522.
