New paper in Chemical Research in Toxicology

Differential DNA melting (left) and genotoxicity (right) induced by silver nanoparticles coated with anionic citrate and cationic branched polyethyleneimine and by graphene oxide nanosheets.

Angela and colleagues have recently published  in Chemical Research in Toxicology their work revealing a connection between DNA-nanoparticle (NP) binding and in vitro DNA damage induced by citrate- and branched polyethylenimine-coated silver nanoparticles (c-AgNPs and b-AgNPs) as well as graphene oxide (GO) nanosheets. This study facilitates our understanding of the effects of NP chemical composition, surface charge, and morphology on DNA stability and genotoxicity, with implications ranging from nanotoxicology to nanobiotechnology and nanomedicine.

You can find out more in: Chemical Research in Toxicology, doi: 10.1021/acs.chemrestox.5b00052